If you want to switch to the speakers connected to your AirPort Express® base stations or if you want to connect to shared libraries via Remote Buddy, you need to have support for assistive devices turned on.
Here's how:
- Open /Applications/System Preferences.app
- Click on the "Universal Access" icon (filled, blue circle with stylized human in the middle)
- Make sure the checkbox "Enable access for assistive devices" is checked. You find it at the bottom of the Univeral Access pane.